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John Levine

Dr. John Levine is Assistant Clinical Professor of Psychiatry at Harvard Medical School. He is a Principal Research Associate in Neuroscience at The Center for Engineering and Medicine at Massachusetts General Hospital, and is an Attending Child Psychiatrist on the staffs of Massachusetts General Hospital and Shriner's Burns Hospital.

He also has a private practice in child, adolescent and adult psychiatry in Wellesley. He has clinical expertise in the evaluation and treatment of children's psychiatric responses to burn injuries, as well children with autism and other neuropsychiatric conditions

Dr. Levine completed his undergraduate training at Cornell University, his Ph.D. in Psychology at University of Miami, and his M.D. at the University of Massachusetts Medical School. He completed his Adult Psychiatry residency at the University of Massachusetts Medical School, and his Child and Adolescent Fellowship at Cambridge Hospital. He completed neuroscience fellowships at McLean Hospital's Laboratory for Neuroplasticity and at the Massachusetts General Hospital.

Dr. Levine's research focuses on developmental neuroscience. The current research has two aims.  First, he is examining neuronal development in the prefrontal cortex in response to environmental stressors and in animal models of developmental disorders.  Second, he is examining pharmacological interventions and other treatment strategies to alleviate aberrant early neurodevelopment.  These questions are examined utilizing both animal models and in vitro experiments to characterize neuronal development at the gene expression, protein expression, and cellular levels. 

Recent Publications

Xu ZX, Jung C, Higgins C, Levine JB, Kong J. Mitochondrial degeneration in ALS. J Bioenergetics and Biomembranes 2004, 36: 395-399

LevineJB, Martin G, Wilson A, Treistman SN. Clozapine inhibits isolated NMDA receptors expressed in xenopus oocytes in a subunit specific manner. Neuroscience Letters, 2003, 346: 125-12

Lachyankar MB, Condon PJ, Daou M,De AK, Levine JB, Axel Obermeier A,Ross AH. Novel Functional Interactions between Trk Kinase and p75 Neurotrophin Receptor in Neuroblastoma Cells. J of Neuroscience Research, 2003, 71: 157-172

Levine JB, Kong J, Nadler M, Xu Z. Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS).  Glia, 1999,28:215-24.

Levine JB, Gruber SA, Baird AA, Yurgelun-Todd DA.  Obsessive-compulsive disorder among schizophrenic patients:  An exploratory study using fMRI data.  Comprehensive Psychiatry 1998; 39: 308-311.

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