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Quan Zhang

Dr. Zhang received his Ph.D. in Biomedical Engineering at Xi’an Jiaotong University, China in 1997, and completed his post-doctoral fellowships at the Department of Radiology at the University of Pennsylvania and at Massachusetts General Hospital. Dr. Zhang received his Harvard Medical School Instructor appointment in 2004, and joined the Center for Engineering in Medicine in 2006.

Dr. Zhang has extensive experience in biomedical optics, electronics and imaging science and technology. He has performed research on optical breast cancer detection, long-term ambulatory monitoring for the diagnosis of acid reflux and non-cardiac chest pain. Currently Dr. Zhang is especially interested in the interactions between cells and lasers, and the in vivo monitoring of tissue growth. His work focuses on techniques for triggering cells to repair themselves, and the selective targeting of the retinal pigment epithelium for the treatment of macular degeneration diseases. Dr. Zhang is also interested and involved in the noninvasive monitoring of brain pathology such as hematoma and ischemia, and prevention of stroke using near-infrared spectroscopy and diffuse optical imaging.


Publications

Quan Zhang, Thomas J. Brukilacchio, Ang Li, Jonathan J. Stott, Tina Chaves, Tao Wu, Richard H. Moore, Daniel B. Kopans, David A. Boas, Co-registered Tomographic X-ray and Optical Breast Imaging: The Initial Results, Journal of Biomedical Optics, 10(2): 024033. 2005.

Ang Li, Q. Zhang, J.P. Culver, E.L. Miller, D.A. Boas, Reconstructing Chromophore Concentration Images Directly by Continuous-Wave Diffuse Optical Tomography, Opitcs Letters, 2004, 29(3), 256-258

Adam B. Milstein, Seungseok Oh, Kevin J. Webb, Charles A. Bouman, Quan Zhang, David A. Boas,  R. P. Millane, Fluorescence Optical Diffusion Tomography, Applied Optics, 2003, 42(16): 3081- 3094

Boas D.A, Brooks D.H., Miller E.L., DiMarzio C.A., Kilmer M., Gaudette R.J. and Zhang Q. Imaging the body with diffuse optical tomography. IEEE Signal Processing Magazine 18(6): 57-75 (2001).

D M Hueber, M A Franceschini, H Y Ma, Q Zhang, J R Ballesteros, S Fantini, D Wallace, V Ntziachristos and B Chance, Non-invasive and quantitative near-infrared haemoglobin spectrometry in the piglet brain during hypoxic stress, using a frequency-domain multi-distance instrument, Phys. Med. Biol. 2001,46(1), 41-62

Quan Zhang, Hong Y. Ma, Shoko Nioka, Britton Chance, Study of near infrared technology for intracranial hematoma detection, Journal of Biomedical Optics, 2000, 5(2), 206-213


Patents

Quan Zhang, Gary Strangman, Electro-optical system, apparatus, and method for ambulatory monitoring, (Pending), USA

David A. Boas, Quan Zhang, Ang Li, Systems and method for generating an image, No. 20030190066 (Pending), USA

Quan Zhang, Chongxun Zheng, Song Zhang, Multi-point pH Probe with Internal Reference for in vivo gastrointestinal monitoring: No.97 2 08372.3, China

Quan Zhang, Chongxun Zheng, Song Zhang, Multi-point pH Probe with External Reference for in vivo gastrointestinal monitoring: No.97 2 08374.X, China




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