Koby joined the Center for Engineering in Medicine in August of 2004. Since then, he has brought several projects to completion, and he recently chaired the First Annual Methods in Bioengineering Conference organization committee.

His work focuses on the study and establishment of microscale liver tissues using microfabrication and cell patterning. The ultimate goal is to develop advanced liver tissues that will display differentiated function and an in-vivo-like response to challenges such as inflammation and viral infection. He is especially interested in the interactions between endothelial cells and hepatocytes, which have been shown to be important for the development of the mature liver, the differentiation of stem cells along the hepatic linage, and Hepatitis C virus infection.

Barbe L, Tolboom H, Nahmias Y, Berthiaume F, Yarmush ML. In-vitro model of hepatic ischemia/reperfusion injury, manuscript in preparation.

Nahmias Y, Berthiaume F, Yarmush ML. Integration of Technologies for Hepatic Tissue Engineering, accepted for publication Advances in Biochemical Engineering/Biotechnology.

Nahmias Y, Kramvis I, Barbe L, Casali M, Berthiaume F, Yarmush ML. A novel formulation of oxygen carrying-matrix enhances liver specific function of cultured hepatocytes, accepted for publication FASEB.

Nahmias Y, Casali M, Barbe L, Berthiaume F, Yarmush ML, Liver endothelial cells promote LDL-R expression and the uptake of HCV-like particles in primary hepatocytes, Hepatology 2006; 43(2):257-265.

Nahmias Y, Schwartz RE, Hu WS, Verfaillie CM, Odde DJ. Endothelium-mediated hepatocyte recruitment in the establishment of liver-like tissue in vitro, Tissue Engineering 2006; 12(6):1627-1638.

Nahmias Y, Schwartz RE, Verfaillie CM, Odde DJ. Laser-guided direct writing for three-dimensional tissue engineering, Biotechnology and Bioengineering 2005; 92(2):129-136.

Nahmias Y, Arneja A, Tower T, Renn MJ, Odde DJ. Cell Patterning on Biological Gels via Cell Spraying Through a Mask, Tissue Engineering 2005; 5/6 (11): 701-708.