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The Center for Engineering in Medicine [1.5 MB PDF file - be patient]
This is the current booklet describing the work of the CEM and its programs.
Communiqué Magazine is an internal newsletter published by and for the researchers of the Center for Engineering in Medicine. It generally appears twice per year.
Volume 1, Issue 1 [April 2002]
Volume 1, Issue 2 [July 2002]
Volume 2, Issue 1 [April 2003]
Volume 2, Issue 2 [October 2003]
Volume 3, Issue 1 [ April 2004]
Volume 3, Issue 2 [October 2004]
Volume 4, Issue 1 [April 2005]
Volume 4, Issue 2 [Winter 2005]
Volume 5, Issue 1 [Summer/Fall 2006]
Volume 5, Issue 2 [Spring2007]
Volume 6, Issue 1 [Winter 2008]
Click here for a brochure on the Program in Biomedical Engineering and Research Education [PDF format]
The following is a list of selected recent articles from the CEM. Click on any title to view a PDF of the article.
Calvano, S., Xiao, W., Richards, D., Felciano, R., Baker, H., Cho, R., Chen, R., Brownstein, B., Cobb, P., Tschoeke, K., Miller-Graziano, C., Moldawer, L, Mindrinos, M., Davis, R., Tompkins, R., Lowry, S., and the Inflammation and the Host Response to Injury Large-Scale Collaborative Research Program, A network-based analysis of systemic inflammation in humans Nature, October 2005
Cobb, P., Mindrinos, M., Miller-Grazianon, C., Calvano, S., Baker, H., Xiao, W., Laudanski, K., Brownstein, B., Elson, C., Hayden, D., Herndon, D., Lowry, S., Maier, R., Schoenfeld, D., Moldawer, L., Davis, R., Tompkins, R., and the Inflammation and the Host Response to Injury Large-Scale Collaborative Research Program , Application of genome-wide expression analysis to human health and disease, PNAS, December 2004
Irimia, D., Liu, S-Y., Tharp, W., Samadani, A., Toner, M., and Poznansky, M., , Microfluidic system for measuring neutrophil migratory responses to fast switches of chemical gradients, Lab on a Chip, December 2005
Kane, B., Zinner, M., Yarmush, M. and Toner, M. Liver-Specific Functional Studies in a Microfluidic Array of Primary Mammalian Hepatocytes, Analytical Chemistry, Vol. 78, No. 13, June 1, 2006
Sugimachi, K., Roach, K., Rhoads, D., Tompkins, R. and Toner, M., Nonmetabolizable Glucose Compounds Impart Cryotolerance to Primary Rat Hepatocytes, Tissue Engineering, Vol.12, No.3, 2006
Maguire, T., Novik, E., Schloss, R., and Yarmush, M., Alginate_PPL Microencapsulation: Effect on the Differentiation of Embryonic Stem Cells Into Hepatocytes, Biotechnology and Bioengineering, Vol. 93, No. 3., February 20, 2006
Megeed, Z., Winters, R., and Yarmush, M., Modulation of Single-Chain Antibody Affinity with Temperature-Responsive Elastin-Like Polypeptide Linkers, Biomacromolecules, Vol. 7, No. 4, April, 2006
Nahmias, Y., Casali, M., Barbe, L., Berthiaume, F., and Yarmush, M., Liver Endothelial Cells Promote LDL-F Expression and the Uptake of HCV-Like Particles in Primary Rat and Human Hepatocytes, Hepatology, Vol. 43, No. 2, February, 2006
Novik, E., Maguire, T., Orlova, K., Schloss, R., and Yarmush, M., Embryoid Body-Mediated Differentiation of Mouse Embryonic Stem Cells Along a Hepatocyte Lineage: Insights from Gene Expression Profiles, Tissue Engineering, Vol. 12, No. 6, 2006
Park, J., Berthiaume, F., Toner, M., Yarmush, M., and Tilles, A., Microfabricated Grooved Substrates as Platforms for Bioartificial Liver Reactors, Biotechnology and Bioengineering, Vol. 90, No. 5, June 2005
Pregibon, D., Toner, M., and Doyle, P., Magnetically and Biologically Active Bead-Patterned Hydrogels, Langmuir, Vol. 22, No. 11, 2006
Qian, W-J., Jacobs, J., Camp, D., Monroe, M., Moore, R., Gritsenko, M., Calvano, S., Lowry, S., Xiao, W., Moldawer, L., Davis, R., Tompkins, R., and Smith, R., Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry, Proteomics, 2005, 5
Revzin, A., Rajagopalan, P., Tilles, A., Berthiaume, F., Yarmush, M., and Toner, M., Designing a Hepatocellular Microenvironment with Protein Microarraying and Poly(ethylene glycol) Photolithography, Langmuir, 2004, Vol. 20, No. 8, 2004
Sethu, P., Moldawer, L., Mindrinos, M., Scumpia, P., Tannahill, C., Wilhelmy, J., Brownstein, B., Tompkins, R., and Toner, M., Microfluidic Isolation of Leukocytes from Whole Blood for Phenotype and Gene Expression Analysis, Analytic Chemistry, Vol. 78, No. 15, August 2006
Storey, J., Xiao, W., Leek, J., Tompkins, R., and Davis, R., Significance analysis of time course microarray experiments, PNAS, Vol, 102, No. 36, September 6, 2005
Thompson, D., King, K., Wieder, K., Toner, M., Yarmush, M., and Jayaraman, A., Dynamic Gene Expression Profiling Using a Microfabricated Living Cell Array, Analytical Chemistry, Vol, 76, No. 14, July 15, 2004
Demirci, U., and Toner, M., Direct etch method for microfluidic channel and nanoheight post-fabrication by picoliter droplets, Applied Physics Letters, 88, 2006
Vemula, M., Berthiaume, F., Jayaraman, A., and Yarmush, M., Expression profiling Analysis of the metabolic and inflammatory changes following burn injury in rates, Physiological Genomics, 18, September 8, 2006
Weider, K., King, K., Thompson, D., Zia, C., Yarmush, M., and Jayaraman, A., Optimization of Reporter Cells for Expression Profiling in a Microfluidic Device, Biomedical Microdevices, 7, 2005
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